Synthesis and structure determination of heterocycles of special pharmaceutical interest.
NMR, mass spectrometric,
and computational investigations.
List
of publications - 2002.
Structural Chemistry Group
Laboratory of Organic Chemistry and Chemical Biology
Department
of Chemistry, University of Turku
Zelenin, K. N.; Potapov, A. A.; Lagoda, I. V.; Alekseev, V. V.; Sinkkonen, J.; Pihlaja, K.
First case of ring-chain tautomerism of N-unsubstituted 1,2,3,4-tetrahydroquinazolines.
Chemistry of Heterocyclic Compounds (New York, NY, United
States)(Translation of Khimiya Geterotsiklicheskikh Soedinenii)
(2002), 38(9), 1148-1149.
Sinkkonen, Jari; Ovcharenko, Vladimir; Zelenin, Kirill N.; Bezhan,
Irina P.; Chakchir, Boris A.; Al-Assar, Fatema; Pihlaja, Kalevi.
Stereoisomerism and ring-chain tautomerism in
1-hydroxy-2,3-dihydro-1H-pyrazolo[1,2-a]pyridazine-5,8-diones and
1-hydroxy- and
1-amino-2,3-dihydro-1H-pyrazolo[1,2-b]phthalazine-5,10-diones.
European Journal of Organic Chemistry (2002), (20), 3447-3454.
Fodor, Lajos; Bernath, Gabor; Sinkkonen, Jari; Pihlaja, Kalevi.
Synthesis and structural characterization of 4H-1,3-benzothiazine derivatives.
Journal of Heterocyclic Chemistry (2002), 39(5), 927-931.
Zelenin, Kirill N.; Lagoda, Igor V.; Alekseyev, Valeriy V.; Sinkkonen, Jari; Shaikhutdinov, Roustem A.; Pihlaja, Kalevi.
Recyclizations of 2-aminobenzylimines and thioaroylhydrazones of N-substituted N-hydroxy-3-oxobutanamides.
Journal of Heterocyclic Chemistry (2002), 39(4), 805-810.
Sinkkonen, Jari; Ovcharenko, Vladimir; Zelenin, Kirill N.; Bezhan,
Irina P.; Chakchir, Boris A.; Al-Assar, Fatema; Pihlaja, Kalevi.
1H and 13C NMR study of
1-hydrazino-2,3-dihydro-1H-pyrazolo[1,2-a]pyridazine-5,8-diones and
-1H-pyrazolo[1,2-b]phthalazine-5,10-diones and their ring-chain
tautomerism.
European Journal of Organic Chemistry (2002), (13), 2046-2053.
Zelenin, K. N.; Alekseyev, V. V.; Pihlaja, K.; Ovcharenko, V. V.
Molecular design of tautomeric interconversions of heterocycles.
Russian Chemical Bulletin (Translation of Izvestiya Akademii Nauk, Seriya Khimicheskaya) (2002), 51(2), 205-221.
Klika, Karel D.; Janovec, Ladislav; Imrich, Jan; Suchar, Gejza; Kristian, Pavol; Sillanpää, Reijo; Pihlaja, Kalevi.
Regioselective synthesis of 2-imino-1,3-thiazolidin-4-ones by treatment
of N-(anthracen-9-yl)-N'-ethylthiourea with bromoacetic acid
derivatives.
European Journal of Organic Chemistry (2002), (7), 1248-1255.
Pihlaja, Kalevi; Klika, Karel D.; Sinkkonen, Jari; Ovcharenko, Vladimir
V.; Maloshitskaya, Olga; Sillanpää, Reijo; Czombos, Jozsef.
Synthesis and Structural Characterization of Cis- and Trans-Fused
4a,5,6,7,8,8a-Hexahydro-2H,4H-1,3-benzodithiines and Their 2-Methyl and
2,2-Dimethyl Derivatives.
Journal of Organic Chemistry (2002), 67(6), 1910-1917.
Pihlaja, Kalevi; Ovcharenko, Vladimir; Kolehmainen, Erkki; Laihia,
Katri; Fabian, Walter M. F.; Dehne, Heinz; Perjessy, Alexander; Kleist,
Marion; Teller, Joachim; Sustekova, Zora.
A correlative IR, MS, 1H, 13C and 15N NMR and theoretical study of 4-arylthiazol-2(3H)-ones.
Journal of the Chemical Society, Perkin Transactions 2 (2002), (2), 329-336.
Starke, I.; Sarodnick, G.; Ovcharenko, V. V.; Pihlaja, K.; Kleinpeter, E.
Evidence for an aryl migration during the electron impact induced fragmentation of substituted aryloxymethylquinoxalines.
Rapid Communications in Mass Spectrometry (2002), 16(3), 169-175.
Tähtinen, Petri; Sinkkonen, Jari; Klika, Karel D.; Nieminen,
Ville; Stajer, Geza; Szakonyi, Zsolt; Fulop, Ferenc; Pihlaja, Kalevi.
1H, 13C, and 15N NMR stereochemical study of cis-fused 7a(8a)-methyl
and 6-phenyl octa(hexa)hydrocyclopenta[d][1,3]oxazines and
[3,1]benzoxazines.
Chirality (2002), 14(2/3), 187-198.