Synthesis and structure determination of heterocycles of special pharmaceutical interest.
NMR, mass spectrometric, and computational investigations.

List of publications (incomplete) - 2005.
Structural Chemistry Group

Laboratory of Organic Chemistry and Chemical Biology
Department of Chemistry, University of Turku

Gawinecki, Ryszard; Kolehmainen, Erkki; Kuczek, Agnieszka; Pihlaja, Kalevi; Osmialowski, Borys.
Complex tauto- and rotamerism of 2-(R-phenyl)-1,2,3,4-tetrahydroquinazolines.
Journal of Physical Organic Chemistry (2005), 18(8), 737-742.

Geci, Imrich; Valtamo, Pauliina; Imrich, Jan; Kivelä, Henri; Kristian, Pavol; Pihlaja, Kalevi.
Regiospecific synthesis, structure and electron ionization mass spectra of 1,3-thiazolidin-4-ones containing the acridine skeleton.
Journal of Heterocyclic Chemistry (2005), 42(5), 907-918.

Kivelä, Henri; Zalan, Zita; Tähtinen, Petri; Sillanpää, Reijo; Fülöp, Ferenc; Pihlaja, Kalevi.
Synthesis and conformational analysis of saturated 3,1,2-benzoxazaphosphinine 2-oxides.
European Journal of Organic Chemistry (2005), (6), 1189-1200.

Kleinpeter, Erich; Koch, Andreas; Pihlaja, Kalevi.
Application of 1 J(C,H) coupling constants in conformational analysis.
Tetrahedron (2005), 61(31), 7349-7358.

Klika, Karel D.; Imrich, Jan; Danihel, Ivan; Boehm, Stanislav; Kristian, Pavol; Hamul'akova, Slavka; Pihlaja, Kalevi; Koch, Andreas; Kleinpeter, Erich.
Configuration and E/Z interconversion mechanism of O(S)-allyl-S(O)-methyl-N-(acridin-9-yl)iminothiocarbonate.
Magnetic Resonance in Chemistry (2005), 43(5), 380-388.

Maloshitskaya, Olga A.; Sinkkonen, Jari; Alekseyev, Valery V.; Zelenin, Kirill N.; Pihlaja, Kalevi.
A comparison of ring-chain tautomerism in heterocycles derived from 2-aminobenzenesulfonamide and anthranilamide.
Tetrahedron (2005), 61(30), 7294-7303.

Mäki, Jukka; Tähtinen, Petri; Kronberg, Leif; Klika, Karel D.
Restricted rotation/tautomeric equilibrium and determination of the site and extent of protonation in bi-imidazole nucleosides by multinuclear NMR and GIAO-DFT calculations.
Journal of Physical Organic Chemistry (2005), 18(3), 240-249.

Oksman, Pentti; Csomos, Peter; Fülöp, Ferenc; Ovcharenko, Vladimir; Kivelä, Henri; Pihlaja, Kalevi.
Stereochemical effects in the EI mass spectra of cis- and transfused octa/hexahydro-3.1-benzoxazines and -benzothiazines.
ARKIVOC (Gainesville, FL, United States) (2005), (4), 39-48.