Publications

Published peer-reviewed articles

  1. Leino O K, Forsbacka N, Laaksonen I E, Mäkelä K T, Matilainen M & Ekman E M (2024): Changing treatment of hip fractures in Finland, Archives of Orthopaedic and Trauma Surgery, 144, 3469–3478.
  2. Hallinen M, Sallinen H, Keskinen H, Matilainen M & Ekman, E (2024): Regional variations in incidence and treatment trends of Achilles tendon ruptures in Finland : a nationwide study, Acta Orthopaedica, 95, 401–406.
  3. Alzghool O M, Aarnio R, Helin J S, Wahlroos S, Keller T, Matilainen M, Solis J, Danon J J, Kassiou M, Snellman A, Solin O, Rinne J O & Haaparanta-Solin M (2024): Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA, EJNMMI Research, 14, 25.
  4. Laaksonen S, Saraste M, Nylund M, Hinz R, Snellman A, Rinne J, Matilainen M & Airas L (2024): Sex-driven variability in TSPO-expressing microglia in MS patients and healthy individuals, Frontiers in Neurology, 20(15), 1352116.
  5. Flumian L, Matilainen M, Nordhausen K & Taskinen S (2024): Stationary subspace analysis based on second-order statistics, Journal of Computational and Applied Mathematics, 436, 115379.
  6. Waggan I, Rissanen E, Tuisku J, Matilainen M, Parkkola R, Rinne J O & Airas L (2023): Adenosine A2A receptor availability in cerebral gray and white matter of patients with Parkinson’s disease, Parkinsonism & Related Disorders, 113, 105766.
  7. Polvinen E, Matilainen M, Nylund M, Sucksdorff M & Airas L M (2023): TSPO-detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis, Neurology – Neuroimmunology & Neuroinflammation, 10(5), e200133.
  8. Laaksonen S, Saraste M, Sucksdorff M, Nylund M, Vuorimaa A, Matilainen M, Heikkinen J & Airas L (2023): Early prognosticators of later TSPO-PET-measurable microglial activation in multiple sclerosis, Multiple Sclerosis and Related Disorders, 75, 104755.
  9. Lehto J, Nylund M, Matilainen M, Sucksdorff M, Vuorimaa A, Rajander J, Wahlroos S, Hariri P & Airas L (2023): Longitudinal stability of progression-related microglial activity during teriflunomide treatment in patients with multiple sclerosis, European Journal of Neurology, 30, 2365-2375.
  10. Saraste M, Matilainen M, Vuorimaa A, Laaksonen S, Sucksdorff M, Leppert D, Kuhle J & Airas L (2023): Association of serum neurofilament light with microglial activation in multiple sclerosis, Journal of Neurology, Neurosurgery & Psychiatry.
  11. Lehto J, Sucksdorff M, Nylund M, Raitanen R, Matilainen M & Airas L (2023): PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report, Journal of Neurology, 270, 2329-2332.
  12. Misin O, Matilainen M, Nylund M, Honkonen E, Rissanen E, Sucksdorff M & Airas L (2022): Innate Immune Cell–Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis, Neurology – Neuroimmunology & Neuroinflammation, 9(4), e1182.
  13. Saraste M, Matilainen M, Rajda C, Galla Z, Sucksdorff M, Vécsei L & Airas L (2022): Association between microglial activation and serum kynurenine pathway metabolites in multiple sclerosis patients, Multiple Sclerosis and Related Disorders, 59, 103667.
  14. Vainio S K, Dickens A M, Matilainen M, López-Picón F R, Aarnio R, Eskola O, Solin O, Anthony D C, Rinne J O, Airas L & Haaparanta-Solin M (2022): Dimethyl fumarate decreases short-term but not long-term inflammation in a focal EAE model of neuroinflammation, EJNMMI Research, 12, 6.
  15. Nylund N, Sucksdorff M, Matilainen M, Polvinen E, Tuisku J & Airas L (2021): Phenotyping of multiple sclerosis lesions according to innate immune cell activation using 18 kDa translocator protein-PET, Brain communications, 22, 4(1), fcab301.
  16. Nordhausen K, Matilainen M, Miettinen J, Virta J & Taskinen S (2021): Dimension Reduction for Time Series in a Blind Source Separation Context Using R, Journal of Statistical Software, 98(15), 1–30.
  17. Waggan I, Rissanen E, Tuisku J, Matilainen M, Helin S, Parkkola R, Rinne J. O. & Airas L (2021): Effect of dopaminergic medication on adenosine 2A receptor availability in patients with Parkinson’s disease, Parkinsonism and Related Disorders, 86, 40-44.
  18. Saraste M, Bezukladova S, Matilainen M, Sucksdorff M, Kuhle J, Leppert D & Airas L (2021): Increased serum glial fibrillary acidic protein associates with microstructural white matter damage in multiple sclerosis. Multiple Sclerosis and Related Disorders, 50, 102810.
  19. Pan Y, Matilainen M, Taskinen S & Nordhausen K (2021): A review of second‐order blind identification methods, WIREs Computational Statistics, e1550.
  20. Hemmilä M, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto A-P, Kettunen J, Pamilo K, Mäkelä K T (2021): Implant survival of 2,723 vitamin E-infused highly crosslinked polyethylene liners in total hip arthroplasty: data from the Finnish Arthroplasty Register, Acta Orthopaedica, 92(3), 316–322.
  21. Saraste M, Bezukladova S, Matilainen M, Tuisku J, Rissanen E, Sucksdorff M, Laaksonen S, Vuorimaa A, Kuhle J, Leppert D & Airas L (2021): High serum neurofilament associates with diffuse white matter damage in MS, Neurology – Neuroimmunology & Neuroinflammation, 8(1), e926.
  22. Saraste M, Bezukladova S, Sucksdorff M, Saunavaara V, Rissanen E, Matilainen M & Airas L (2020): Fingolimod treatment reverses signs of diffuse white matter damage in multiple  sclerosis: A pilot study, Multiple Sclerosis and Related Disorders, 48, 102690.
  23. Smith E, Jaakonmäki N, Nylund M, Kupila L, Matilainen M & Airas L (2020): Frequency and etiology of acute transverse myelitis in Southern Finland, Multiple Sclerosis and Related Disorders, 46, 102652.
  24. Sucksdorff M, Matilainen M, Tuisku J, Polvinen E, Vuorimaa A, Rokka J, Nylund M, Rissanen E & Airas L (2020): Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis, Brain, 143(11), 3318–3330.
  25. Palomäki A, Hemmilä M, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto A-P, Kettunen J, Manninen M & Mäkelä K T (2020): Implant Survival of 6,080 Tritanium Cups in Primary Total Hip Arthroplasty: Data from the Finnish Arthroplasty Register from 2009 to 2017, The Journal of Bone and Joint Surgery, 102(13), 1177-1185.
  26. Bezukladova S, Tuisku J, Matilainen M, Vuorimaa A, Nylund M, Smith S, Sucksdorff M, Mohammadian M, Saunavaara V, Laaksonen S, Rokka J, Rinne J O, Rissanen E & Airas L (2020): Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging, Neurology – Neuroimmunology & Neuroinflammation, 7 (3), e691.
  27. Airas L, Nylund M, Mannonen I, Matilainen M, Sucksdorff M & Rissanen E (2020): Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland, Multiple Sclerosis and Related Disorders, 40, 101980.
  28. Miettinen J, Matilainen M, Nordhausen K & Taskinen S (2020): Extracting Conditionally Heteroskedastic Components Using Independent Component Analysis, Journal of Time Series Analysis, 41, 293-311.
  29. Högel H, Rissanen E, Barro C, Matilainen M, Nylund M, Kuhle J & Airas L (2020): Serum Glial Fibrillary Acidic Protein Correlates with Multiple Sclerosis Disease Progression, Multiple Sclerosis Journal, 6(2), 210-219.
  30. Sucksdorff M, Tuisku J, Matilainen M, Vuorimaa A, Smith S, Keitilä J, Rokka J, Parkkola R, Nylund M, Rinne J, Rissanen E & Airas L (2019): Natalizumab treatment reduces microglial activation in the white matter of the MS brain, Neurology – Neuroimmunology Neuroinflammation, 6(4), e574.
  31. Matilainen M, Croux C, Nordhausen K & Oja H (2019): Sliced Average Variance Estimation for Multivariate Time Series, Statistics, 53(3), 630-655.
  32. Hemmilä M M, Karvonen M, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto A-P, Kettunen J, Manninen M & Mäkelä K T (2019): Survival of 11,390 Continuum cups in primary total hip arthroplasty based on data from the Finnish Arthroplasty Register, Acta Orthopaedica, 90 (4), 312-317.
  33. Matilainen M, Nordhausen K & Virta J (2018): On the number of signals in multivariate time series, Proceedings of International Conference on Latent Variable Analysis and Signal Separation (LVA/ICA), 248-258.
  34. Montonen E, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto A P, Leskinen J, Kettunen J, Manninen M, & Mäkelä K T (2018): What Is the Long-term Survivorship of Cruciate-retaining TKA in the Finnish Registry?, Clinical Orthopaedics and Related Research, 476 (6), 1205-1211.
  35. Matilainen M, Croux C, Nordhausen K & Oja H (2017): Supervised dimension reduction for multivariate time series, Econometrics and Statistics, 4, 57-69.
  36. Matilainen M, Miettinen J, Nordhausen K, Oja H & Taskinen S (2017): On Independent Component Analysis with Stochastic Volatility Models, Austrian Journal of Statistics, 46 (3-4), 57-66.
  37. Palomäki A, Lempainen L, Matilainen M, Eskelinen A, Remes V, Virolainen P & Mäkelä K T (2017), Survival of uncemented cups from a single manufacturer implanted from 1985 to 2013: Finnish Arthroplasty Register data, Archives of Orthopaedic and Trauma Surgery, pp. 1-10.
  38. Matilainen M, Miettinen J, Nordhausen K, Oja H & Taskinen S (2016): ICA and Stochastic Volatility Models. In Aivazian S, Filzmoser P and Kharin Y: “Proceedings of the XI International Conference on Computer Data Analysis and Modeling”, 30-37, Publishing Center of BSU, Minsk.
  39. Toyinbo O, Matilainen M, Turunen M, Putus T, Shaughnessy R & Haverinen-Shaughnessy U (2016): Modeling Associations between Principals’ Reported Indoor Environmental Quality and Students’ Self-Reported Respiratory Health Outcomes Using GLMM and ZIP Models, International Journal of Environmental Research and Public Health, 13 (4), 385, 1-12.
  40. Matilainen M, Nordhausen K & Oja H (2015): New Independent Component Analysis Tools for Time Series. Statistics and Probability Letters, 105, 80-87.
  41. Mäkelä K T, Matilainen M, Pulkkinen P, Fenstad A M, Havelin L I, Engesaeter L, Furnes O, Overgaard S, Pedersen A B, Kärrholm J, Malchau H, Garellick G, Ranstam J & Eskelinen A (2014), Countrywise results of total hip arthroplasty: an analysis of 438,733 hips based on the Nordic Arthroplasty Register Association database, Acta Orthopaedica, 85 (2), 107-116.
  42. Mäkelä K T, Matilainen M, Pulkkinen P, Fenstad A M, Havelin L, Engesaeter L, Furnes O, Pedersen A B, Overgaard S, Kärrholm J, Malchau H, Garellick G, Ranstam J & Eskelinen A (2014): Failure rate of cemented and uncemented total hip replacement: a register study of combined Nordic database of four nations, BMJ, 348.
  43. Junnila M, Kostensalo I, Virolainen P, Remes V, Matilainen M, Vahlberg T, Pulkkinen P, Eskelinen A, Itälä A & Mäkelä K (2014): Hip resurfacing arthroplasty versus large head metal on metal total hip arthroplasty: comparison of three designs from the Finnish Arthroplasty Register, Scandinavian Journal of Surgery, 103, 54-59.
  44. Kostensalo I, Junnila M, Virolainen P, Remes V, Matilainen M, Vahlberg T, Pulkkinen P, Eskelinen A & Mäkelä K T (2013): Effect of femoral head size on risk of revision for dislocation after total hip arthroplasty: A population-based analysis of 42,379 primary procedures from the Finnish Arthroplasty Register, Acta Orthopaedica, 84 (4), 342-347.

Software

Theses

  • Matilainen M (2018): On Independent Component Analysis and Supervised Dimension Reduction for Time Series, Doctoral dissertation, University of Turku.
  • Matilainen M (2013): Yleistetyt lineaariset sekamallit ja Zero Inflated Poisson -mallit oppilaiden oireiden mallintamisessa (Generalized linear mixed models and Zero Inflated Poisson models in the modelling of students’ symptoms), Master’s thesis in statistics, University of Turku.
  • Matilainen M (2011): ARIMA-malleista ja niiden sovelluksista lämpötila-aikasarjoihin (On ARIMA models and their applications to temperature time series), Master’s thesis in applied mathematics, University of Turku.
  • Matilainen M (2011): Pólyan lause (Pólya’s Theorem), Bachelor’s thesis in mathematics, University of Turku.